Startseite2022-04-21T11:42:01+00:00

Defining the
osteohepatic
axis in iron
metabolism
Summary Iron deficiency and iron overload are both associated with bone loss and an increased risk of fracture, which markedly limit mobility and autonomy of affected individuals. Thus, iron levels must be balanced to maintain health in general, and in particular bone strength. The DFG-funded FerrOs consortium (FOR5146) brings together experts of iron and bone metabolism to decipher the underlying mechanisms of iron regulation and its interactions with bone. Funded by

Collaboration of

To find out more about the projects and the scientists involved in FerrOs, please see:

Projects
Team

Research Blog & News

April 23 is International FOP Awareness Day 2022!!

Since the University of Pennsylvania announced their breakthrough discovery of the FOP gene ACVR1 at April 23, 2006, this date is now celebrated as International FOP Awareness Day! This year marks the 16th anniversary of the discovery of the FOP gene meaning 16 years of hope, progress and determination to find a cure.

April 23, 2022|

Congratulations to Andrea Burden, Ph.D., Recipient of the 2021 Emerging Leader in Pharmaceutical Sciences

The Leslie Dan Faculty of Pharmacy from University of Toronto, Canada, awarded six Alumni Awards (https://www.pharmacy.utoronto.ca/news-announcements/exceptional-alumni-recognized-through-second-annual-alumni-awards) in different categories recognizing the remarkable achievements of alumni in pharmacy practice and pharmaceutical sciences.

March 31, 2022|

New publication by FerrOs researchers!

We proudly present the new article by Silvia Colucci, Sandro Altamura and Martina Muckenthaler from our FerrOs Research Group on "Liver Sinusoidal Endothelial Cells Suppress Bone Morphogenetic Protein 2 Production in Response to TGFβ Pathway Activation" that was just published in Hepatology (https://pubmed.ncbi.nlm.nih.gov/33982327/).

October 6, 2021|

2nd FerrOs Webinar: Delphine Meynard on Matriptase-2 as a therapeutic target

Our second FerrOs Webinar took place on September 28th. The FerrOs members were very keen on listening to the excellent talk of Delphine Meynard, who presented her newest work on the role of matripase-2 as a novel therapeutic target in diseases with ineffective hematopoiesis. Besides the stimulating talk, it was great to see each other again and get to know new members of the FerrOs consortium.

September 30, 2021|

New FerrOs review: “Shaping the bone through iron and iron-related proteins”

We proudly present our new review on "Shaping the bone through iron and iron-related proteins" that was just published in Seminars in Hematology  (https://doi.org/10.1053/j.seminhematol.2021.06.002).

July 20, 2021|

1st FerrOs Retreat: Getting to know each other!

Meetings during pandemic times – on June 4th we met online at our 1st FerrOs Retreat. Although we were not able to meet face-to-face, we were all very happy to “see” each other online and listen to the eight FerrOs projects so all new members could see what is planned and to discuss how we can interact during the next four years.

June 8, 2021|
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