Team

Maja Vujic Spasic

Peter Steele-Perkins

P1: Maja Vujic Spasic (Ulm)

Project title: Role of iron in bone metabolism of Hfe-hemochromatosis

Team: Peter Steele-Perkins (PhD student)

Professor for Molecular Endocrinology & Deputy Director of the Institute of Comparative Molecular EndocrinologyInstitute of Comparative Molecular Endocrinology
University of Ulm
Helmholtzstr. 8/1
89081 Ulm, Germany

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Tel: +49 731 50-32635

Key words: Hfe, iron, bone

Andrea Steinbicker

Isabelle Hornung

Fatemeh Eizadi Fard

Lisa Schrader

Guiscard Seebohm

Nathalie Strutz-Seebohm

Anne Humberg

P2: Andrea Steinbicker (Köln) & Guiscard Seebohm (Münster)

Project title: P2: 4-“T”-interplay (Type I BMP receptors/TFR1/TFR2/TMPRSS6) in iron sensing and bone homeostasis

Team: Isabelle Hornung (PhD student), Fatemeh Eizadi Fard (PhD student), Lisa Schrader (associated Post Doc), Anne Humberg (technician), Nathalie Strutz-Seebohm (Group leader)

Univ.-Prof. Dr. Andrea Steinbicker

Direktorin der Klinik für Anästhesiologie und Operative Intensivmedizin

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Tel: +49 221 478-82054

Key words: BMP signaling, iron, inflammation

Professor for Cellular Electrophysiology and Molecular Biology

Department of Cardiology
University of Münster
Albert-Schweitzer-Campus 1, Gebäude A1
48149 Münster, Germany

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Tel: +49 (0) 251 / 83-58255

Key words: Protein-protein interactions

Martina Rauner

Vanessa Passin

P3: Martina Rauner (Dresden)

Project title: Deconstructing cell metabolic pathways causing iron toxicity-induced inhibition of osteoblast function, induction of FGF-23 and osteomalacia

Team: Vanessa Passin (PhD student)

Professor for Molecular Bone Biology

Department of Medicine III & Center for Healthy Aging
Technische Universität Dresden
Fetscherstr. 74
01307 Dresden, Germany

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Tel: +49 351 4584206

Key words: Bone, BMP signaling

Ulrike Baschant

Sven Spangenberg

P4: Ulrike Baschant (Dresden)

Project title: Defining the role of the iron-sensor Tfr2 in ossification processes

Team: Sven Spangenberg (PhD student)

Department of Medicine III & Center for Healthy Aging

Technische Universität Dresden
Fetscherstr. 74
01307 Dresden, Germany

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Tel: +49 351 45817595

Key words: Bone, HO, inflammation

Martina Muckenthaler

Ana Pego

Stefania Cucinelli

Ruiyue Qiu

Anja Schuh

P5: Martina Muckenthaler (Heidelberg)

Project title: Identification of iron-related signals controlling BMP expression in liver non-parenchymal cells

Team: Ana Pego (PostDoc), Ruiyue Qiu (PostDoc), Stefania Cucinelli (PhD student), Anja Schuh (Clinician Scientist)

Professor for Molecular Medicine

University of Heidelberg
Department of Pediatric Hematology, Oncology and Immunology
Im Neuenheimer Feld 350
69120 Heidelberg, Germany

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Tel: +49 6221 56-6923

Key words: Iron homeostasis and sensing, Fpn-hepcidin axis

Sandro Altamura

Lorenz Hofbauer

Tiago Carvalho Oliveira

Claudia Krause

P6: Sandro Altamura (Heidelberg) & Lorenz Hofbauer (Dresden)

Project title: Molecular mechanisms of ferroportin-mediated protection against bone diseases

Team: Tiago Carvalho Oliveira (PhD student), Claudia Krause (technician)

University of Heidelberg

Department of Pediatric Hematology, Oncology and Immunology
Im Neuenheimer Feld 350
69120 Heidelberg, Germany

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Tel: 06221 56-8839

Key words: Iron, Fpn

Professor of Medicine & Director of the Center for Healthy Aging

Department of Medicine III & Center for Healthy Aging
Technische Universität Dresden
Fetscherstr. 74
01307 Dresden, Germany

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Tel: +49 351 4583173

Key words: Bone, osteoporosis

Ursula Klingmüller

Marcel Schilling

Clara Hennersdorf

Philipp Kastl

P7: Ursula Klingmüller (Heidelberg)

Project title: Employing a systems biology approach to unravel organism-wide and hepatocyte-specific iron-dependent mechanisms regulating BMP signal transduction

Team: Clara Hennersdorf (PhD student), Marcel Schilling (PostDoc), Philipp Kastl (PostDoc)

Professor for Systems Biology of Signal Transduction

German Cancer Research Center (DKFZ)
Systems Biology of Signal Transduction
Im Neuenheimer Feld 280
69120 Heidelberg, Germany

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Tel: +49 6221-424481

Key words: Systems biology, iron homeostasis

Andrea Burden

Andrea Steinbicker

Lorenz Hofbauer

Marcel Rauer

P8: Andrea Burden (Zürich), Andrea Steinbicker (Köln) & Lorenz Hofbauer (Dresden) 

Project title: Impact of iron overload and anemia on fractures

Team: Marcel Rauer (Clinician Scientist)

Professor for Pharmacoepidemiology

Institute of Pharmaceutical Sciences
ETH Zurich, HCI H407
Vladimir-Prelog-Weg 4
CH-8093 Zurich, Switzerland

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Tel: +41 44 633 74 09

Key words: Pharmacoepidemiology, drug safety

Univ.-Prof. Dr. Andrea Steinbicker

Direktorin der Klinik für Anästhesiologie und Operative Intensivmedizin

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Tel: +49 221 478-82054

Key words: BMP signaling, iron, inflammation

Professor of Medicine & Director of the Center for Healthy Aging

Department of Medicine III & Center for Healthy Aging
Technische Universität Dresden
Fetscherstr. 74
01307 Dresden, Germany

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Tel: +49 351 4583173

Key words: Bone, osteoporosis

María Ledesma-Colunga

Yelda Yüregir

P9: María Ledesma-Colunga (Dresden) 

Project title: Exploring TFR2 as a central hub of mitochondrial metabolism within the liver-bone-inflammation axis

Team: Yelda Yüregir

Department of Medicine III & Center for Healthy Aging

Technische Universität Dresden
Fetscherstr. 74
01307 Dresden, Germany

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Tel: +49 351 458 2035

Key words: Iron metabolism, Inflammation